General Information of the Compound
Compound ID
CP0535833
Compound Name
10-[2-(4-Benzyloxy-phenyl)-acetyl]-1,8-dihydroxy-10H-anthracen-9-one
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Structure
Formula
C29H22O5
Molecular Weight
450.49
Canonical SMILES
Oc1cccc2C(C(=O)Cc3ccc(OCc4ccccc4)cc3)c3cccc(O)c3C(=O)c12
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InChI
InChI=1S/C29H22O5/c30-23-10-4-8-21-26(22-9-5-11-24(31)28(22)29(33)27(21)23)25(32)16-18-12-14-20(15-13-18)34-17-19-6-2-1-3-7-19/h1-15,26,30-31H,16-17H2
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InChIKey
YIVXRIKQEZBYQB-UHFFFAOYSA-N
Physicochemical Property
logP
5.1649
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
83.83
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10366494
SID: 15379981
ChEMBL ID
CHEMBL130038
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00205, 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 = 600 nM
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