General Information of the Compound
Compound ID
CP0533869
Compound Name
1-[[5-(methoxymethyl)-2-(trifluoromethoxy)phenyl]methyl]-3-(8-methyl-2-phenylimidazo[1,2-a]pyrazin-3-yl)urea
    Show/Hide
Structure
Formula
C24H22F3N5O3
Molecular Weight
485.466
Canonical SMILES
COCc1ccc(OC(F)(F)F)c(CNC(=O)Nc2c(nc3c(C)nccn23)-c2ccccc2)c1
    Show/Hide
InChI
InChI=1S/C24H22F3N5O3/c1-15-21-30-20(17-6-4-3-5-7-17)22(32(21)11-10-28-15)31-23(33)29-13-18-12-16(14-34-2)8-9-19(18)35-24(25,26)27/h3-12H,13-14H2,1-2H3,(H2,29,31,33)
    Show/Hide
InChIKey
KNZNJSNITSGMNY-UHFFFAOYSA-N
Physicochemical Property
logP
5.07142
Rotatable Bonds
7
Heavy Atom Count
35
Polar Areas
89.78
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 146672948
ChEMBL ID
CHEMBL4861572