General Information of the Compound
Compound ID
CP0533824
Compound Name
N-[4-[2-chloro-5-(trifluoromethyl)phenyl]phenyl]-2,6-difluorobenzamide
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Structure
Formula
C20H11ClF5NO
Molecular Weight
411.757
Canonical SMILES
Fc1cccc(F)c1C(=O)Nc1ccc(cc1)-c1cc(ccc1Cl)C(F)(F)F
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InChI
InChI=1S/C20H11ClF5NO/c21-15-9-6-12(20(24,25)26)10-14(15)11-4-7-13(8-5-11)27-19(28)18-16(22)2-1-3-17(18)23/h1-10H,(H,27,28)
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InChIKey
OHHIGBIGGBDEJY-UHFFFAOYSA-N
Physicochemical Property
logP
6.5563
Rotatable Bonds
3
Heavy Atom Count
28
Polar Areas
29.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11418465
SID: 16515037
ChEMBL ID
CHEMBL4857063
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03664, Interleukin-2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 8 nM
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