General Information of the Compound
Compound ID
CP0533542
Compound Name
3-{4-chloro-3-[(N-methyl-1,5-dimethyl-1H-pyrazole-4-sulfonamido)methyl]phenyl}-3-(1-methyl-1H-1,2,3-benzotriazol-5-yl)propanoic acid
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Structure
Formula
C23H25ClN6O4S
Molecular Weight
517.011
Canonical SMILES
CN(Cc1cc(ccc1Cl)C(CC(O)=O)c1ccc2n(C)nnc2c1)S(=O)(=O)c1cnn(C)c1C
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InChI
InChI=1S/C23H25ClN6O4S/c1-14-22(12-25-29(14)3)35(33,34)28(2)13-17-9-15(5-7-19(17)24)18(11-23(31)32)16-6-8-21-20(10-16)26-27-30(21)4/h5-10,12,18H,11,13H2,1-4H3,(H,31,32)
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InChIKey
SRPXGGSRYJJWSO-UHFFFAOYSA-N
Physicochemical Property
logP
3.09092
Rotatable Bonds
8
Heavy Atom Count
35
Polar Areas
123.21
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118170531
ChEMBL ID
CHEMBL4542179
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03126, Kelch-like ECH-associated protein 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 320 nM
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