General Information of the Compound
Compound ID
CP0531866
Compound Name
3-cyano-N-(3-(3-isopropoxypropyl)-6-(morpholine-4-carbonyl)-3H-imidazo[4,5-b]pyridin-2-yl)benzamide
    Show/Hide
Structure
Formula
C25H28N6O4
Molecular Weight
476.537
Canonical SMILES
CC(C)OCCCn1c(NC(=O)c2cccc(c2)C#N)nc2cc(cnc12)C(=O)N1CCOCC1
    Show/Hide
InChI
InChI=1S/C25H28N6O4/c1-17(2)35-10-4-7-31-22-21(14-20(16-27-22)24(33)30-8-11-34-12-9-30)28-25(31)29-23(32)19-6-3-5-18(13-19)15-26/h3,5-6,13-14,16-17H,4,7-12H2,1-2H3,(H,28,29,32)
    Show/Hide
InChIKey
QUJQUFYFSOCPCW-UHFFFAOYSA-N
Physicochemical Property
logP
2.84278
Rotatable Bonds
8
Heavy Atom Count
35
Polar Areas
122.37
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 52943490
ChEMBL ID
CHEMBL1269900
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS