General Information of the Compound
Compound ID
CP0530957
Compound Name
(2S)-2-[(2,4,6-trimethoxyphenyl)methylamino]butanedioic acid
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Structure
Formula
C14H19NO7
Molecular Weight
313.306
Canonical SMILES
COc1cc(OC)c(CN[C@@H](CC(O)=O)C(O)=O)c(OC)c1
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InChI
InChI=1S/C14H19NO7/c1-20-8-4-11(21-2)9(12(5-8)22-3)7-15-10(14(18)19)6-13(16)17/h4-5,10,15H,6-7H2,1-3H3,(H,16,17)(H,18,19)/t10-/m0/s1
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InChIKey
NTRBVPZOYSLWDP-JTQLQIEISA-N
Physicochemical Property
logP
0.7299
Rotatable Bonds
9
Heavy Atom Count
22
Polar Areas
114.32
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 134153213
ChEMBL ID
CHEMBL3970451
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02255, Proto-oncogene tyrosine-protein kinase Src
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000214 BV-2 Mus musculus (Mouse)  1
1
IC50 = 14400 nM
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