General Information of the Compound
Compound ID
CP0529719
Compound Name
3-cyano-N-(3-pentyl-6-(piperidine-1-carbonyl)-3H-imidazo[4,5-b]pyridin-2-yl)benzamide
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Structure
Formula
C25H28N6O2
Molecular Weight
444.539
Canonical SMILES
CCCCCn1c(NC(=O)c2cccc(c2)C#N)nc2cc(cnc12)C(=O)N1CCCCC1
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InChI
InChI=1S/C25H28N6O2/c1-2-3-5-13-31-22-21(15-20(17-27-22)24(33)30-11-6-4-7-12-30)28-25(31)29-23(32)19-10-8-9-18(14-19)16-26/h8-10,14-15,17H,2-7,11-13H2,1H3,(H,28,29,32)
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InChIKey
DKWNMYDVXCDZAI-UHFFFAOYSA-N
Physicochemical Property
logP
4.37158
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
103.91
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 52943279
ChEMBL ID
CHEMBL1270917
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 904 nM
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