General Information of the Compound
Compound ID
CP0525745
Compound Name
[(1R,2R,6R,10S,11R,15R,17R)-6-hydroxy-4,17-dimethyl-5-oxo-1-phenylmethoxy-15-prop-1-en-2-yl-12,14-dioxatetracyclo[8.7.0.02,6.011,15]heptadeca-3,8-dien-8-yl]methyl benzoate
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Structure
Formula
C35H38O7
Molecular Weight
570.682
Canonical SMILES
C[C@@H]1C[C@@]2(OCO[C@@H]2[C@@H]2C=C(COC(=O)c3ccccc3)C[C@@]3(O)[C@@H](C=C(C)C3=O)[C@@]12OCc1ccccc1)C(C)=C
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InChI
InChI=1S/C35H38O7/c1-22(2)34-17-24(4)35(41-20-25-11-7-5-8-12-25)28(31(34)40-21-42-34)16-26(18-33(38)29(35)15-23(3)30(33)36)19-39-32(37)27-13-9-6-10-14-27/h5-16,24,28-29,31,38H,1,17-21H2,2-4H3/t24-,28+,29-,31-,33-,34-,35-/m1/s1
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InChIKey
JHOOCSCMNNFKSE-UYCPPTJOSA-N
Physicochemical Property
logP
5.3492
Rotatable Bonds
7
Heavy Atom Count
42
Polar Areas
91.29
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44430073
ChEMBL ID
CHEMBL391807
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 25.5 nM
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