General Information of the Compound
Compound ID
CP0522346
Compound Name
N-[(6-methoxy-9-methyl-1,2,3,4-tetrahydrocarbazol-4-yl)methyl]-4-(trifluoromethoxy)benzamide
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Structure
Formula
C23H23F3N2O3
Molecular Weight
432.442
Canonical SMILES
COc1ccc2n(C)c3CCCC(CNC(=O)c4ccc(OC(F)(F)F)cc4)c3c2c1
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InChI
InChI=1S/C23H23F3N2O3/c1-28-19-11-10-17(30-2)12-18(19)21-15(4-3-5-20(21)28)13-27-22(29)14-6-8-16(9-7-14)31-23(24,25)26/h6-12,15H,3-5,13H2,1-2H3,(H,27,29)
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InChIKey
WFOZZHQRAQTUTE-UHFFFAOYSA-N
Physicochemical Property
logP
4.9354
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
52.49
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44447671
ChEMBL ID
CHEMBL398539
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 490 nM
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