General Information of the Compound
Compound ID
CP0521867
Compound Name
2-[5-methyl-3-(4-methyl-1,3-thiazol-2-yl)-4-oxochromen-7-yl]oxyacetic acid
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Structure
Formula
C16H13NO5S
Molecular Weight
331.349
Canonical SMILES
Cc1csc(n1)-c1coc2cc(OCC(O)=O)cc(C)c2c1=O
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InChI
InChI=1S/C16H13NO5S/c1-8-3-10(21-6-13(18)19)4-12-14(8)15(20)11(5-22-12)16-17-9(2)7-23-16/h3-5,7H,6H2,1-2H3,(H,18,19)
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InChIKey
ZEIRIYJTRSQIFR-UHFFFAOYSA-N
Physicochemical Property
logP
2.99674
Rotatable Bonds
4
Heavy Atom Count
23
Polar Areas
89.63
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 707926
ChEMBL ID
CHEMBL2030681
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
2
Ki = 2238.72 nM
   TI
   LI
   LO
   TS