General Information of the Compound
Compound ID
CP0520289
Compound Name
CHEMBL1915248
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Formula
C24H30ClN3O3
Molecular Weight
443.975
Canonical SMILES
CO[C@H]1CC[C@@H](CC1)NC(=O)c1cc(C)n(Cc2cc(Cl)cc3cc(oc23)C(C)C)n1
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InChI
InChI=1S/C24H30ClN3O3/c1-14(2)22-12-16-10-18(25)11-17(23(16)31-22)13-28-15(3)9-21(27-28)24(29)26-19-5-7-20(30-4)8-6-19/h9-12,14,19-20H,5-8,13H2,1-4H3,(H,26,29)/t19-,20-
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InChIKey
JGPDUNCFJGZLAS-MXVIHJGJSA-N
Physicochemical Property
logP
5.45022
Rotatable Bonds
6
Heavy Atom Count
31
Polar Areas
69.29
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
SID: 49707667
ChEMBL ID
CHEMBL1915248
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01205, Prostaglandin E2 receptor EP1 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 316.23 nM
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