General Information of the Compound
Compound ID
CP0515541
Compound Name
(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-phenylethyl)-piperidine-4-yl)-methanol
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Structure
Formula
C23H30FNO3
Molecular Weight
387.495
Canonical SMILES
COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccccc2)CC1
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InChI
InChI=1S/C23H30FNO3/c1-27-23-20(8-5-9-21(23)28-17-13-24)22(26)19-11-15-25(16-12-19)14-10-18-6-3-2-4-7-18/h2-9,19,22,26H,10-17H2,1H3
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InChIKey
URDKULLWSBXHPQ-UHFFFAOYSA-N
Physicochemical Property
logP
4.0316
Rotatable Bonds
9
Heavy Atom Count
28
Polar Areas
41.93
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44582739
ChEMBL ID
CHEMBL490846
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01492, 5-hydroxytryptamine receptor 2A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000744 GF62 Epinephelus awoara (Yellow grouper)  1
1
Ki = 1.63 nM
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