General Information of the Compound
| Compound ID |
CP0515037
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| Compound Name |
N4-cyclopropyl-N2-(quinolin-6-yl)-5-(trifluoromethyl) pyrimidine-2,4-diamine
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| Structure |
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| Formula |
C17H14F3N5
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| Molecular Weight |
345.328
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| Canonical SMILES |
FC(F)(F)c1cnc(Nc2ccc3ncccc3c2)nc1NC1CC1
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| InChI |
InChI=1S/C17H14F3N5/c18-17(19,20)13-9-22-16(25-15(13)23-11-3-4-11)24-12-5-6-14-10(8-12)2-1-7-21-14/h1-2,5-9,11H,3-4H2,(H2,22,23,24,25)
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| InChIKey |
GWRHBTXTQFLVSP-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02366, Serine/threonine-protein kinase ULK1
Protein ID: PT01177, Serine/threonine-protein kinase ULK2