General Information of the Compound
Compound ID
CP0514732
Compound Name
2-(5-chlorofuran-2-yl)-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethoxy)-[1,2,4]triazolo[1,5-c]pyrimidin-5-amine
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Structure
Formula
C24H28ClN7O4
Molecular Weight
513.986
Canonical SMILES
COCCOc1ccc(cc1)N1CCN(CCOc2cc3nc(nn3c(N)n2)-c2ccc(Cl)o2)CC1
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InChI
InChI=1S/C24H28ClN7O4/c1-33-14-15-34-18-4-2-17(3-5-18)31-10-8-30(9-11-31)12-13-35-22-16-21-27-23(19-6-7-20(25)36-19)29-32(21)24(26)28-22/h2-7,16H,8-15H2,1H3,(H2,26,28)
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InChIKey
KJQHWCLBOHLQRT-UHFFFAOYSA-N
Physicochemical Property
logP
2.8461
Rotatable Bonds
10
Heavy Atom Count
36
Polar Areas
116.41
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
11
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 23540126
ChEMBL ID
CHEMBL475592
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 40 nM
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