General Information of the Compound
Compound ID
CP0507410
Compound Name
methyl (2S)-2-[[5-[(2-bromophenyl)methoxy]-4-oxochromene-2-carbonyl]amino]-3-methylbutanoate
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Formula
C23H22BrNO6
Molecular Weight
488.334
Canonical SMILES
COC(=O)[C@@H](NC(=O)c1cc(=O)c2c(OCc3ccccc3Br)cccc2o1)C(C)C
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InChI
InChI=1S/C23H22BrNO6/c1-13(2)21(23(28)29-3)25-22(27)19-11-16(26)20-17(9-6-10-18(20)31-19)30-12-14-7-4-5-8-15(14)24/h4-11,13,21H,12H2,1-3H3,(H,25,27)/t21-/m0/s1
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InChIKey
RSBYILJKKPQKCG-NRFANRHFSA-N
Physicochemical Property
logP
4.0619
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
94.84
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4754283
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02718, Broad substrate specificity ATP-binding cassette transporter ABCG2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 50 nM
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