General Information of the Compound
Compound ID
CP0506160
Compound Name
1,8-Dihydroxy-10-[3-(4-hydroxy-phenyl)-propionyl]-10H-anthracen-9-one
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Structure
Formula
C23H18O5
Molecular Weight
374.392
Canonical SMILES
Oc1ccc(CCC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1
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InChI
InChI=1S/C23H18O5/c24-14-10-7-13(8-11-14)9-12-19(27)20-15-3-1-5-17(25)21(15)23(28)22-16(20)4-2-6-18(22)26/h1-8,10-11,20,24-26H,9,12H2
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InChIKey
BXBHHHFQVYLVCG-UHFFFAOYSA-N
Physicochemical Property
logP
3.6816
Rotatable Bonds
4
Heavy Atom Count
28
Polar Areas
94.83
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10339370
SID: 15350661
ChEMBL ID
CHEMBL132621
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00205, 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 = 1000 nM
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