General Information of the Compound
| Compound ID |
CP0506099
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| Compound Name |
(R)-N-(2-(4'-(2-(methylsulfonamido)ethyl)biphenyl-4-yl)propyl)propane-2-sulfonamide
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| Synonyms |
AMPA agonists (Alzheimer's Disease), Lilly
AMPA receptor agonist (agitation in Alzheimer's Disease), Eli Lilly
LY-450108
LY-451395
Mibampator
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| Structure |
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| Formula |
C21H30N2O4S2
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| Molecular Weight |
438.615
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| Canonical SMILES |
CC(C)S(=O)(=O)NC[C@H](C)c1ccc(cc1)-c1ccc(CCNS(C)(=O)=O)cc1
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| InChI |
InChI=1S/C21H30N2O4S2/c1-16(2)29(26,27)23-15-17(3)19-9-11-21(12-10-19)20-7-5-18(6-8-20)13-14-22-28(4,24)25/h5-12,16-17,22-23H,13-15H2,1-4H3/t17-/m0/s1
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| InChIKey |
ULRDYYKSPCRXAJ-KRWDZBQOSA-N
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| CAS |
375345-95-2
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound