General Information of the Compound
Compound ID
CP0504976
Compound Name
JMC506554 Compound 1m
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Structure
Formula
C24H22N2O2
Molecular Weight
370.452
Canonical SMILES
Oc1ccc2[nH]cc(CCNC(=O)Cc3cccc(c3)-c3ccccc3)c2c1
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InChI
InChI=1S/C24H22N2O2/c27-21-9-10-23-22(15-21)20(16-26-23)11-12-25-24(28)14-17-5-4-8-19(13-17)18-6-2-1-3-7-18/h1-10,13,15-16,26-27H,11-12,14H2,(H,25,28)
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InChIKey
HDZNSBAISQLELX-UHFFFAOYSA-N
Physicochemical Property
logP
4.4419
Rotatable Bonds
6
Heavy Atom Count
28
Polar Areas
65.12
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
2
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24749374
SID: 49651497
ChEMBL ID
CHEMBL238274
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 430 nM
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