General Information of the Compound
Compound ID
CP0504304
Compound Name
2-(furan-2-yl)-N7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-N7-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine
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Structure
Formula
C25H32N8O3
Molecular Weight
492.584
Canonical SMILES
COCCOc1ccc(cc1)N1CCN(CCN(C)c2cc3nc(nn3c(N)n2)-c2ccco2)CC1
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InChI
InChI=1S/C25H32N8O3/c1-30(22-18-23-27-24(21-4-3-15-36-21)29-33(23)25(26)28-22)9-10-31-11-13-32(14-12-31)19-5-7-20(8-6-19)35-17-16-34-2/h3-8,15,18H,9-14,16-17H2,1-2H3,(H2,26,28)
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InChIKey
WFIRIJPVGZUJGN-UHFFFAOYSA-N
Physicochemical Property
logP
2.2501
Rotatable Bonds
10
Heavy Atom Count
36
Polar Areas
110.42
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
11
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 23540125
ChEMBL ID
CHEMBL480756
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2.5 nM
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   LI
   LO
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