General Information of the Compound
Compound ID
CP0503421
Compound Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]butanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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Structure
Formula
C41H55N11O7
Molecular Weight
813.961
Canonical SMILES
CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
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InChI
InChI=1S/C41H55N11O7/c1-2-29(49-39(58)32(22-27-15-8-4-9-16-27)48-35(54)25-47-34(53)24-42)37(56)52-33(23-28-17-10-5-11-18-28)40(59)50-30(19-12-20-46-41(44)45)38(57)51-31(36(43)55)21-26-13-6-3-7-14-26/h3-11,13-18,29-33H,2,12,19-25,42H2,1H3,(H2,43,55)(H,47,53)(H,48,54)(H,49,58)(H,50,59)(H,51,57)(H,52,56)(H4,44,45,46)/t29-,30-,31-,32-,33-/m0/s1
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InChIKey
BLPGOOVQJIDZLB-ZTTXAYQISA-N
Physicochemical Property
logP
-1.8377
Rotatable Bonds
24
Heavy Atom Count
59
Polar Areas
308.11
Hydrogen Bond Donor Count
10
Hydrogen Bond Acceptor Count
9
Complexity
59

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 53363625
SID: 125266557
ChEMBL ID
CHEMBL1802370
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05331, Pyroglutamylated RF-amide peptide receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 355 nM
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