General Information of the Compound
Compound ID
CP0503419
Compound Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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Structure
Formula
C40H53N11O7
Molecular Weight
799.934
Canonical SMILES
C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
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InChI
InChI=1S/C40H53N11O7/c1-25(47-38(57)31(21-27-14-7-3-8-15-27)48-34(53)24-46-33(52)23-41)36(55)51-32(22-28-16-9-4-10-17-28)39(58)49-29(18-11-19-45-40(43)44)37(56)50-30(35(42)54)20-26-12-5-2-6-13-26/h2-10,12-17,25,29-32H,11,18-24,41H2,1H3,(H2,42,54)(H,46,52)(H,47,57)(H,48,53)(H,49,58)(H,50,56)(H,51,55)(H4,43,44,45)/t25-,29-,30-,31-,32-/m0/s1
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InChIKey
ZBSAAMDSCGKHSJ-PKAIDYEGSA-N
Physicochemical Property
logP
-2.2278
Rotatable Bonds
23
Heavy Atom Count
58
Polar Areas
308.11
Hydrogen Bond Donor Count
10
Hydrogen Bond Acceptor Count
9
Complexity
58

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56666433
ChEMBL ID
CHEMBL1802412
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05331, Pyroglutamylated RF-amide peptide receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1308 nM
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