General Information of the Compound
Compound ID
CP0502279
Compound Name
3-cyano-N-(3-(3-methoxyphenyl)-6-(piperidine-1-carbonyl)-3H-imidazo[4,5-b]pyridin-2-yl)benzamide
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Structure
Formula
C27H24N6O3
Molecular Weight
480.528
Canonical SMILES
COc1cccc(c1)-n1c(NC(=O)c2cccc(c2)C#N)nc2cc(cnc12)C(=O)N1CCCCC1
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InChI
InChI=1S/C27H24N6O3/c1-36-22-10-6-9-21(15-22)33-24-23(14-20(17-29-24)26(35)32-11-3-2-4-12-32)30-27(33)31-25(34)19-8-5-7-18(13-19)16-28/h5-10,13-15,17H,2-4,11-12H2,1H3,(H,30,31,34)
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InChIKey
IKYDCWPNZBDRTP-UHFFFAOYSA-N
Physicochemical Property
logP
4.17918
Rotatable Bonds
5
Heavy Atom Count
36
Polar Areas
113.14
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 52949423
ChEMBL ID
CHEMBL1271432
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 325 nM
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