General Information of the Compound
Compound ID
CP0497768
Compound Name
2-(3-cyanobenzamido)-3-(3-methoxypropyl)-3H-imidazo[4,5-b]pyridine-6-carboxamide
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Structure
Formula
C19H18N6O3
Molecular Weight
378.392
Canonical SMILES
COCCCn1c(NC(=O)c2cccc(c2)C#N)nc2cc(cnc12)C(N)=O
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InChI
InChI=1S/C19H18N6O3/c1-28-7-3-6-25-17-15(9-14(11-22-17)16(21)26)23-19(25)24-18(27)13-5-2-4-12(8-13)10-20/h2,4-5,8-9,11H,3,6-7H2,1H3,(H2,21,26)(H,23,24,27)
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InChIKey
OPULSPRBRMLXIN-UHFFFAOYSA-N
Physicochemical Property
logP
1.69068
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
135.92
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 52949461
ChEMBL ID
CHEMBL1270509
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2430 nM
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