General Information of the Compound
Compound ID
CP0497027
Compound Name
4-(2,5-dimethoxyphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide
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Structure
Formula
C28H39N3O3
Molecular Weight
465.638
Canonical SMILES
COc1ccc(OC)c(c1)N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1
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InChI
InChI=1S/C28H39N3O3/c1-33-23-14-15-27(34-2)26(21-23)31-19-17-30(18-20-31)16-7-3-4-13-28(32)29-25-12-8-10-22-9-5-6-11-24(22)25/h5-6,9,11,14-15,21,25H,3-4,7-8,10,12-13,16-20H2,1-2H3,(H,29,32)
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InChIKey
HBXLJWDMQIUMDH-UHFFFAOYSA-N
Physicochemical Property
logP
4.58
Rotatable Bonds
10
Heavy Atom Count
34
Polar Areas
54.04
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11478226
ChEMBL ID
CHEMBL374297
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01746, 5-hydroxytryptamine receptor 7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 70.3 nM
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