General Information of the Compound
Compound ID
CP0495008
Compound Name
US9120798, Comparator 1
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Structure
Formula
C35H45N5
Molecular Weight
535.78
Canonical SMILES
CC(C)(C)CN1CCC2(CC1)CCN(c1ccccc1Nc1nc3ccc(cc3[nH]1)C(C)(C)C)c1ccccc21
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InChI
InChI=1S/C35H45N5/c1-33(2,3)24-39-20-17-35(18-21-39)19-22-40(30-13-9-7-11-26(30)35)31-14-10-8-12-28(31)37-32-36-27-16-15-25(34(4,5)6)23-29(27)38-32/h7-16,23H,17-22,24H2,1-6H3,(H2,36,37,38)
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InChIKey
AONJWECSJOZDAI-UHFFFAOYSA-N
Physicochemical Property
logP
8.5255
Rotatable Bonds
4
Heavy Atom Count
40
Polar Areas
47.19
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59337700
ChEMBL ID
CHEMBL3942314
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01877, P2Y purinoceptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 258.8 nM
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