General Information of the Compound
Compound ID
CP0494111
Compound Name
1-(2-imino-3-(2-(piperidin-1-yl)ethyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-3,3-dimethylbutan-2-ol
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Structure
Formula
C20H32N4O
Molecular Weight
344.503
Canonical SMILES
CC(C)(C)C(O)Cn1c2ccccc2n(CCN2CCCCC2)c1=N
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InChI
InChI=1S/C20H32N4O/c1-20(2,3)18(25)15-24-17-10-6-5-9-16(17)23(19(24)21)14-13-22-11-7-4-8-12-22/h5-6,9-10,18,21,25H,4,7-8,11-15H2,1-3H3
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InChIKey
MWCSFYNDOUZTLZ-UHFFFAOYSA-N
Physicochemical Property
logP
2.81517
Rotatable Bonds
5
Heavy Atom Count
25
Polar Areas
57.18
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 2868621
ChEMBL ID
CHEMBL397851
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02415, Sodium/glucose cotransporter 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 > 50000 nM
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   LI
   LO
   TS