General Information of the Compound
| Compound ID |
CP0493236
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| Compound Name |
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]isoquinoline-3-carboxamide
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| Structure |
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| Formula |
C29H29N3O3
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| Molecular Weight |
467.569
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| Canonical SMILES |
COc1cc2CCN(CCc3ccc(NC(=O)c4cc5ccccc5cn4)cc3)Cc2cc1OC
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| InChI |
InChI=1S/C29H29N3O3/c1-34-27-16-22-12-14-32(19-24(22)17-28(27)35-2)13-11-20-7-9-25(10-8-20)31-29(33)26-15-21-5-3-4-6-23(21)18-30-26/h3-10,15-18H,11-14,19H2,1-2H3,(H,31,33)
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| InChIKey |
RJSOUZKIJXBVSO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01546, ATP-dependent translocase ABCB1
Protein ID: PT02718, Broad substrate specificity ATP-binding cassette transporter ABCG2