General Information of the Compound
Compound ID
CP0492345
Compound Name
(3,5-dimethylphenyl)methyl 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoate
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Structure
Formula
C23H23NO5
Molecular Weight
393.439
Canonical SMILES
Cc1cc(C)cc(COC(=O)c2cc(NCc3cc(O)ccc3O)ccc2O)c1
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InChI
InChI=1S/C23H23NO5/c1-14-7-15(2)9-16(8-14)13-29-23(28)20-11-18(3-5-22(20)27)24-12-17-10-19(25)4-6-21(17)26/h3-11,24-27H,12-13H2,1-2H3
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InChIKey
VFBKLVOROFEVPG-UHFFFAOYSA-N
Physicochemical Property
logP
4.38934
Rotatable Bonds
6
Heavy Atom Count
29
Polar Areas
99.02
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
6
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10475666
SID: 15499360
ChEMBL ID
CHEMBL169356
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00922, Epidermal growth factor receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000520 39ER22 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
2
IC50 = 3000 nM
   TI
   LI
   LO
   TS