General Information of the Compound
Compound ID
CP0492310
Compound Name
5-[(4-phenyldiazenylphenyl)methyl]-1,3-thiazolidine-2,4-dione
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Formula
C16H13N3O2S
Molecular Weight
311.366
Canonical SMILES
O=C1NC(=O)C(Cc2ccc(cc2)\N=N\c2ccccc2)S1
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InChI
InChI=1S/C16H13N3O2S/c20-15-14(22-16(21)17-15)10-11-6-8-13(9-7-11)19-18-12-4-2-1-3-5-12/h1-9,14H,10H2,(H,17,20,21)/b19-18+
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InChIKey
BPUOMPSSHWYLDN-VHEBQXMUSA-N
Physicochemical Property
logP
3.9961
Rotatable Bonds
4
Heavy Atom Count
22
Polar Areas
70.89
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4762401
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 2200 nM
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