General Information of the Compound
| Compound ID |
CP0492050
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| Compound Name |
2-[[4-hydroxy-2-oxo-1-[[6-(trifluoromethyl)pyridin-3-yl]methyl]-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonyl]amino]acetic acid
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| Structure |
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| Formula |
C18H16F3N3O6
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| Molecular Weight |
427.335
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| Canonical SMILES |
OC(=O)CNC(=O)c1c(O)c2COCCc2n(Cc2ccc(nc2)C(F)(F)F)c1=O
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| InChI |
InChI=1S/C18H16F3N3O6/c19-18(20,21)12-2-1-9(5-22-12)7-24-11-3-4-30-8-10(11)15(27)14(17(24)29)16(28)23-6-13(25)26/h1-2,5,27H,3-4,6-8H2,(H,23,28)(H,25,26)
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| InChIKey |
UUPLODLHSLMEQS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02612, Egl nine homolog 1
Protein ID: PT01988, Prolyl hydroxylase EGLN2
Protein ID: PT02885, Prolyl hydroxylase EGLN3