General Information of the Compound
Compound ID
CP0489119
Compound Name
N-[3-(3-methyl-1-naphthalen-2-yl-6-oxopyridazin-4-yl)phenyl]ethanesulfonamide
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Structure
Formula
C23H21N3O3S
Molecular Weight
419.506
Canonical SMILES
CCS(=O)(=O)Nc1cccc(c1)-c1cc(=O)n(nc1C)-c1ccc2ccccc2c1
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InChI
InChI=1S/C23H21N3O3S/c1-3-30(28,29)25-20-10-6-9-19(13-20)22-15-23(27)26(24-16(22)2)21-12-11-17-7-4-5-8-18(17)14-21/h4-15,25H,3H2,1-2H3
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InChIKey
WOJQUKGFGFSIFL-UHFFFAOYSA-N
Physicochemical Property
logP
4.12272
Rotatable Bonds
5
Heavy Atom Count
30
Polar Areas
81.06
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71541767
SID: 163540259
ChEMBL ID
CHEMBL2397337
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00894, Androgen receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 = 9760 nM
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