General Information of the Compound
Compound ID
CP0486914
Compound Name
6-bromo-4-[3-(1,3-dihydroisoindol-2-yl)propyl]-1,4-benzoxazin-3-one
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Structure
Formula
C19H19BrN2O2
Molecular Weight
387.277
Canonical SMILES
Brc1ccc2OCC(=O)N(CCCN3Cc4ccccc4C3)c2c1
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InChI
InChI=1S/C19H19BrN2O2/c20-16-6-7-18-17(10-16)22(19(23)13-24-18)9-3-8-21-11-14-4-1-2-5-15(14)12-21/h1-2,4-7,10H,3,8-9,11-13H2
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InChIKey
FVQBFECXCKFNFT-UHFFFAOYSA-N
Physicochemical Property
logP
3.5804
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
32.78
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118731582
ChEMBL ID
CHEMBL3409388
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01509, Sigma non-opioid intracellular receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
Ki > 100 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS