General Information of the Compound
Compound ID
CP0485563
Compound Name
ethyl 4-(4-hydroxy-5-oxo-3-pentanoyl-2-phenyl-2H-pyrrol-1-yl)benzoate
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Structure
Formula
C24H25NO5
Molecular Weight
407.466
Canonical SMILES
CCCCC(=O)C1=C(O)C(=O)N(C1c1ccccc1)c1ccc(cc1)C(=O)OCC
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InChI
InChI=1S/C24H25NO5/c1-3-5-11-19(26)20-21(16-9-7-6-8-10-16)25(23(28)22(20)27)18-14-12-17(13-15-18)24(29)30-4-2/h6-10,12-15,21,27H,3-5,11H2,1-2H3
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InChIKey
MCFUOUZLUPZJBC-UHFFFAOYSA-N
Physicochemical Property
logP
4.5226
Rotatable Bonds
8
Heavy Atom Count
30
Polar Areas
83.91
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 58045279
ChEMBL ID
CHEMBL4129705
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03393, P2X purinoceptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000093 C6-BU-1 Rattus norvegicus (Rat)  1
1
IC50 = 1020 nM
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