General Information of the Compound
Compound ID
CP0483382
Compound Name
2-(4-(5-Ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2,3-difluorophenyl)-N-(4-(2-hydroxyethoxy)-3-(trifluoromethyl)phenyl)acetamide
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Structure
Formula
C24H21F5N2O5
Molecular Weight
512.431
Canonical SMILES
CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(OCCO)c(c2)C(F)(F)F)c(F)c1F
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InChI
InChI=1S/C24H21F5N2O5/c1-2-35-19-9-14(12-30-23(19)34)16-5-3-13(21(25)22(16)26)10-20(33)31-15-4-6-18(36-8-7-32)17(11-15)24(27,28)29/h3-6,9,11-12,32H,2,7-8,10H2,1H3,(H,30,34)(H,31,33)
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InChIKey
DBAIOFPQXZMYCC-UHFFFAOYSA-N
Physicochemical Property
logP
4.2899
Rotatable Bonds
9
Heavy Atom Count
36
Polar Areas
100.65
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 78426333
ChEMBL ID
CHEMBL3355007