General Information of the Compound
Compound ID
CP0475877
Compound Name
2-(furan-2-yl)imidazo[1,2-a]pyridine
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Structure
Formula
C11H8N2O
Molecular Weight
184.198
Canonical SMILES
c1coc(c1)-c1cn2ccccc2n1
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InChI
InChI=1S/C11H8N2O/c1-2-6-13-8-9(12-11(13)5-1)10-4-3-7-14-10/h1-8H
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InChIKey
SIDJEDFUSPSLPY-UHFFFAOYSA-N
Physicochemical Property
logP
2.5943
Rotatable Bonds
1
Heavy Atom Count
14
Polar Areas
30.44
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
14

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 5244097
SID: 16312664
ChEMBL ID
CHEMBL4128119
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
CC50 > 100000 nM
   TI
   LI
   LO
   TS