General Information of the Compound
| Compound ID |
CP0475642
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| Compound Name |
4-hydroxy-1-[4-methyl-6-[[2-[4-(trifluoromethoxy)phenoxy]acetyl]amino]quinazolin-2-yl]piperidine-4-carboxamide
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| Structure |
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| Formula |
C24H24F3N5O5
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| Molecular Weight |
519.48
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| Canonical SMILES |
Cc1nc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(O)(CC1)C(N)=O
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| InChI |
InChI=1S/C24H24F3N5O5/c1-14-18-12-15(30-20(33)13-36-16-3-5-17(6-4-16)37-24(25,26)27)2-7-19(18)31-22(29-14)32-10-8-23(35,9-11-32)21(28)34/h2-7,12,35H,8-11,13H2,1H3,(H2,28,34)(H,30,33)
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| InChIKey |
MMHXXYWJJXMTSW-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound