General Information of the Compound
Compound ID
CP0473833
Compound Name
(2S)-2-ethoxy-3-[4-[2-[5-methyl-2-(5-phenylthiophen-2-yl)-1,3-oxazol-4-yl]ethoxy]phenyl]propanoic acid
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Structure
Formula
C27H27NO5S
Molecular Weight
477.582
Canonical SMILES
CCO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccc(s2)-c2ccccc2)cc1)C(O)=O
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InChI
InChI=1S/C27H27NO5S/c1-3-31-23(27(29)30)17-19-9-11-21(12-10-19)32-16-15-22-18(2)33-26(28-22)25-14-13-24(34-25)20-7-5-4-6-8-20/h4-14,23H,3,15-17H2,1-2H3,(H,29,30)/t23-/m0/s1
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InChIKey
QFQGNTDOAIPHRN-QHCPKHFHSA-N
Physicochemical Property
logP
6.03222
Rotatable Bonds
11
Heavy Atom Count
34
Polar Areas
81.79
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56673196
ChEMBL ID
CHEMBL1813012
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 22 nM
   TI
   LI
   LO
   TS
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 4.5 nM
   TI
   LI
   LO
   TS