General Information of the Compound
Compound ID
CP0471880
Compound Name
N-(1-(2-(Azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]pyrimidin-4-yl)tetrahydro- 2H-pyran-4-carboxamide hydrochloride
    Show/Hide
Structure
Formula
C19H28N6O2
Molecular Weight
372.473
Canonical SMILES
O=C(Nc1ncnc2n(CCN3CCCCCC3)ncc12)C1CCOCC1
    Show/Hide
InChI
InChI=1S/C19H28N6O2/c26-19(15-5-11-27-12-6-15)23-17-16-13-22-25(18(16)21-14-20-17)10-9-24-7-3-1-2-4-8-24/h13-15H,1-12H2,(H,20,21,23,26)
    Show/Hide
InChIKey
JLLMGLKMXOUBKS-UHFFFAOYSA-N
Physicochemical Property
logP
2.0674
Rotatable Bonds
5
Heavy Atom Count
27
Polar Areas
85.17
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 71223095
ChEMBL ID
CHEMBL4279140
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01509, Sigma non-opioid intracellular receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 514 nM
   TI
   LI
   LO
   TS