General Information of the Compound
| Compound ID |
CP0471822
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| Compound Name |
1-(5-amino-2-fluoropyridin-4-yl)-3-[3-(difluoromethyl)-1,2-thiazol-5-yl]urea
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| Structure |
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| Formula |
C10H8F3N5OS
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| Molecular Weight |
303.269
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| Canonical SMILES |
Nc1cnc(F)cc1NC(=O)Nc1cc(ns1)C(F)F
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| InChI |
InChI=1S/C10H8F3N5OS/c11-7-1-5(4(14)3-15-7)16-10(19)17-8-2-6(9(12)13)18-20-8/h1-3,9H,14H2,(H2,15,16,17,19)
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| InChIKey |
SFJREJRCVVEJQX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03585, Probable global transcription activator SNF2L2
Protein ID: PT03301, Transcription activator BRG1