General Information of the Compound
Compound ID
CP0469796
Compound Name
2-(furan-2-yl)-5-N-[2-(4-methylpiperazin-1-yl)ethyl]-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
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Structure
Formula
C15H21N9O
Molecular Weight
343.395
Canonical SMILES
CN1CCN(CCNc2nc(N)n3nc(nc3n2)-c2ccco2)CC1
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InChI
InChI=1S/C15H21N9O/c1-22-6-8-23(9-7-22)5-4-17-14-19-13(16)24-15(20-14)18-12(21-24)11-3-2-10-25-11/h2-3,10H,4-9H2,1H3,(H3,16,17,18,19,20,21)
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InChIKey
NLHRMBTYEDTOKC-UHFFFAOYSA-N
Physicochemical Property
logP
0.0208
Rotatable Bonds
5
Heavy Atom Count
25
Polar Areas
113.64
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
10
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 121225598
ChEMBL ID
CHEMBL3934661
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 31 nM
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