General Information of the Compound
Compound ID
CP0468973
Compound Name
2-(3-cyanobenzamido)-3-(3-methoxypropyl)-N,N-dimethyl-3H-imidazo[4,5-b]pyridine-6-carboxamide
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Structure
Formula
C21H22N6O3
Molecular Weight
406.446
Canonical SMILES
COCCCn1c(NC(=O)c2cccc(c2)C#N)nc2cc(cnc12)C(=O)N(C)C
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InChI
InChI=1S/C21H22N6O3/c1-26(2)20(29)16-11-17-18(23-13-16)27(8-5-9-30-3)21(24-17)25-19(28)15-7-4-6-14(10-15)12-22/h4,6-7,10-11,13H,5,8-9H2,1-3H3,(H,24,25,28)
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InChIKey
RBAOLDGIUFILHC-UHFFFAOYSA-N
Physicochemical Property
logP
2.29358
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
113.14
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 52942060
ChEMBL ID
CHEMBL1270609
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 123 nM
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