General Information of the Compound
Compound ID
CP0467811
Compound Name
4-[(Z)-(4-Bromophenyl)(ethoxyimino)methyl]-4'-methyl-1'-[(3-methyl-2-pyridinyl)carbonyl]-1,4'-bipiperidine NOxide
    Show/Hide
Structure
Formula
C27H35BrN4O3
Molecular Weight
543.506
Canonical SMILES
CCO\N=C(\C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)ccc[n+]1[O-])c1ccc(Br)cc1
    Show/Hide
InChI
InChI=1S/C27H35BrN4O3/c1-4-35-29-24(21-7-9-23(28)10-8-21)22-11-16-31(17-12-22)27(3)13-18-30(19-14-27)26(33)25-20(2)6-5-15-32(25)34/h5-10,15,22H,4,11-14,16-19H2,1-3H3/b29-24+
    Show/Hide
InChIKey
HSAKOKPUPOVOFH-RMLRFSFXSA-N
Physicochemical Property
logP
4.53842
Rotatable Bonds
6
Heavy Atom Count
35
Polar Areas
72.08
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 9579325
SID: 15956396
ChEMBL ID
CHEMBL317644
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05087, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 16 nM
   TI
   LI
   LO
   TS