General Information of the Compound
Compound ID
CP0466237
Compound Name
(3-cyanophenyl) 4-[(3-methylbenzoyl)amino]benzenesulfonate
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Formula
C21H16N2O4S
Molecular Weight
392.436
Canonical SMILES
Cc1cccc(c1)C(=O)Nc1ccc(cc1)S(=O)(=O)Oc1cccc(c1)C#N
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InChI
InChI=1S/C21H16N2O4S/c1-15-4-2-6-17(12-15)21(24)23-18-8-10-20(11-9-18)28(25,26)27-19-7-3-5-16(13-19)14-22/h2-13H,1H3,(H,23,24)
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InChIKey
ZDBXAGLBYMESDU-UHFFFAOYSA-N
Physicochemical Property
logP
3.8867
Rotatable Bonds
5
Heavy Atom Count
28
Polar Areas
96.26
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4752357
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04714, P2Y purinoceptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
IC50 = 14800 nM
   TI
   LI
   LO
   TS
Protein ID: PT05061, Uracil nucleotide/cysteinyl leukotriene receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS