General Information of the Compound
Compound ID
CP0464809
Compound Name
CHEMBL4127905
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Formula
C27H24N2O6
Molecular Weight
472.497
Canonical SMILES
CCOC(=O)c1ccc(cc1)N1C(C(\C(=N\O)c2ccc(OC)cc2)=C(O)C1=O)c1ccccc1
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InChI
InChI=1S/C27H24N2O6/c1-3-35-27(32)19-9-13-20(14-10-19)29-24(18-7-5-4-6-8-18)22(25(30)26(29)31)23(28-33)17-11-15-21(34-2)16-12-17/h4-16,24,30,33H,3H2,1-2H3/b28-23+
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InChIKey
IRTXRGLPEHQBFJ-WEMUOSSPSA-N
Physicochemical Property
logP
4.6504
Rotatable Bonds
7
Heavy Atom Count
35
Polar Areas
108.66
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4127905
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03393, P2X purinoceptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000093 C6-BU-1 Rattus norvegicus (Rat)  1
1
IC50 = 560 nM
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