General Information of the Compound
Compound ID
CP0461496
Compound Name
9-(2-Benzenesulfonylmethyl-benzyl)-6-furan-2-yl-9H-purin-2-ylamine
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Structure
Formula
C23H19N5O3S
Molecular Weight
445.504
Canonical SMILES
Nc1nc(-c2ccco2)c2ncn(Cc3ccccc3CS(=O)(=O)c3ccccc3)c2n1
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InChI
InChI=1S/C23H19N5O3S/c24-23-26-20(19-11-6-12-31-19)21-22(27-23)28(15-25-21)13-16-7-4-5-8-17(16)14-32(29,30)18-9-2-1-3-10-18/h1-12,15H,13-14H2,(H2,24,26,27)
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InChIKey
LZFWVIFXSFJRRE-UHFFFAOYSA-N
Physicochemical Property
logP
3.6907
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
116.9
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44401558
ChEMBL ID
CHEMBL195503
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 3.1 nM
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