General Information of the Compound
| Compound ID |
CP0457868
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| Compound Name |
(2R)-2-[4-[3-methoxy-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-5-yl]oxy-1-morpholin-4-ylpropan-1-one
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| Structure |
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| Formula |
C28H29N5O5
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| Molecular Weight |
515.57
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| Canonical SMILES |
COc1cc(Nc2ncnc3cccc(O[C@H](C)C(=O)N4CCOCC4)c23)ccc1Oc1ccc(C)nc1
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| InChI |
InChI=1S/C28H29N5O5/c1-18-7-9-21(16-29-18)38-23-10-8-20(15-25(23)35-3)32-27-26-22(30-17-31-27)5-4-6-24(26)37-19(2)28(34)33-11-13-36-14-12-33/h4-10,15-17,19H,11-14H2,1-3H3,(H,30,31,32)/t19-/m1/s1
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| InChIKey |
WZACCHHDKDZYQO-LJQANCHMSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound