General Information of the Compound
| Compound ID |
CP0455609
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| Compound Name |
2-[(6-methylpyridin-2-yl)methoxy]-7-pyridin-3-yloxypyrido[1,2-a]pyrimidin-4-one
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| Structure |
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| Formula |
C20H16N4O3
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| Molecular Weight |
360.373
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| Canonical SMILES |
Cc1cccc(COc2cc(=O)n3cc(Oc4cccnc4)ccc3n2)n1
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| InChI |
InChI=1S/C20H16N4O3/c1-14-4-2-5-15(22-14)13-26-19-10-20(25)24-12-17(7-8-18(24)23-19)27-16-6-3-9-21-11-16/h2-12H,13H2,1H3
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| InChIKey |
XRMJPVIAEPOYKG-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01247, Metabotropic glutamate receptor 5
Protein ID: PT00854, Metabotropic glutamate receptor 5