General Information of the Compound
Compound ID
CP0451696
Compound Name
2-(4-cyanophenoxy)-N-(4-methoxy-7-morpholin-4-yl-1,3-benzothiazol-2-yl)-2-methylpropanamide
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Structure
Formula
C23H24N4O4S
Molecular Weight
452.536
Canonical SMILES
COc1ccc(N2CCOCC2)c2sc(NC(=O)C(C)(C)Oc3ccc(cc3)C#N)nc12
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InChI
InChI=1S/C23H24N4O4S/c1-23(2,31-16-6-4-15(14-24)5-7-16)21(28)26-22-25-19-18(29-3)9-8-17(20(19)32-22)27-10-12-30-13-11-27/h4-9H,10-13H2,1-3H3,(H,25,26,28)
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InChIKey
FNGOZTFMECGBTA-UHFFFAOYSA-N
Physicochemical Property
logP
3.80928
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
96.71
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137643847
ChEMBL ID
CHEMBL4086370
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 58 nM
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