General Information of the Compound
| Compound ID |
CP0449478
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| Compound Name |
N-[2-(4-thiophen-3-ylphenyl)propyl]propane-2-sulfonamide
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| Synonyms |
AMPA modulators, Eli Lilly
LY-392098
LY-404187
LY-4516146
LY-451616
LY-451646
LY-503430
PF-4775874
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| Structure |
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| Formula |
C16H21NO2S2
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| Molecular Weight |
323.483
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| Canonical SMILES |
CC(C)S(=O)(=O)NCC(C)c1ccc(cc1)-c1ccsc1
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| InChI |
InChI=1S/C16H21NO2S2/c1-12(2)21(18,19)17-10-13(3)14-4-6-15(7-5-14)16-8-9-20-11-16/h4-9,11-13,17H,10H2,1-3H3
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| InChIKey |
QFAUPDBCVKBKSH-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound