General Information of the Compound
Compound ID
CP0446629
Compound Name
6-Furan-2-yl-9-naphthalen-1-ylmethyl-9H-purin-2-ylamine
    Show/Hide
Structure
Formula
C20H15N5O
Molecular Weight
341.374
Canonical SMILES
Nc1nc(-c2ccco2)c2ncn(Cc3cccc4ccccc34)c2n1
    Show/Hide
InChI
InChI=1S/C20H15N5O/c21-20-23-17(16-9-4-10-26-16)18-19(24-20)25(12-22-18)11-14-7-3-6-13-5-1-2-8-15(13)14/h1-10,12H,11H2,(H2,21,23,24)
    Show/Hide
InChIKey
KNEBOLCFPUBPIG-UHFFFAOYSA-N
Physicochemical Property
logP
3.87
Rotatable Bonds
3
Heavy Atom Count
26
Polar Areas
82.76
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44401809
ChEMBL ID
CHEMBL193613
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 5.6 nM
   TI
   LI
   LO
   TS